Xfactor how to know about one horse

Understanding pedigrees, inbreeding, dosage, etc.

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Sylvie Hebert
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Xfactor how to know about one horse

Postby Sylvie Hebert » Wed Oct 31, 2012 4:31 pm

how do you find out about the Xfactor?
Secretariat got it from dam side as Dash for Cash did,they are related by Imperatrice but how do you follow it in pedigrees.I know the dams can be XX or Xx but sires only Xx or xx so Dam has to transmit it but is there a way to find out if your particular mare is Xx or XX or else?
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Pan Zareta
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Postby Pan Zareta » Wed Oct 31, 2012 9:26 pm

If you're referring to Haun's hypothesis that heart size is primarily controlled by a gene or genes on the X chromosome be aware that it's contradicted by genomic evidence. Nothing on the X appears to correlate with heart size or effectiveness.

Males have a single X chromosome. They get it from their dam and transmit it only to their daughters. Ergo, any line with no male repeats in the pedigree is potentially contributing to an individual's X chromosome(s). Secretariat and Dash For Cash were one and three generations, respectively, removed from Imperatrice. It's quite possible that they had little or no X in common.

stancaris
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imperatrice is 4 generations removed in tail female

Postby stancaris » Sun Nov 04, 2012 12:53 pm

Pan Zareta: I found Imperatrice to be 4 generations removed from Dash For Cash in her tail-female line.

It is likely that on the average Dash For Cash would inherit 6.25% of the genes carried by Imperatrice (50%, 25%, 12.5%, 6.25%).

Sec gets on the average around 25% of Imperatrice's genes because Imperatrice is Sec's second dam. As you mentioned in an earlier discussion- Imperatrice sends one of her recombined Xs to her daughter Somethingroyal and she in turn sends one of these further recombined Xs to her son Secretariat. Although Dash for Cash only gets around 6% of Imperatrice's Xs he does inherit the same mt-DNA from his tail female line.

The mt-DNA carried by Sec is probably identical to the mt-DNA carried by Dash For Cash since Imperatrice is found in the tail-female line of both of these great sires.

Then again, were there any mixups where one of the above stallions actually does not trace in tail female to Imperatrice???

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Pan Zareta
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Postby Pan Zareta » Sun Nov 04, 2012 9:51 pm

I was counting each dam between Imperatrice and Secretariat (1, Somethingroyal) and Dash For Cash (3, Scattered, Hide And Seek, Find A Buyer) as a generation.

There's no published mtDNA evidence for error in family 2s. And it would be fascinating to know what else DFC and Sec. had in common at the molecular level.