White & flamboyant sires in England

Talk about equine color, markings, genetics, etc. Post pictures of flashy Thoroughbreds!

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xfactor fan
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Postby xfactor fan » Wed Dec 03, 2008 2:36 am

http://www.pubmedcentral.nih.gov/articl ... id=2065884


Here's a link to the Dominant white paper.

Roan, sabino-1, tobiano, and dominant white were independently mapped to a region on equine Chromosome 3 (ECA 3) harboring the KIT gene. Direct quote from the paper.

There are several Dominant white mutations, related in that they are mutations in the same region (KIT) of chromosome 3.


There are probably several Sabino mutations that are related in the same way, minor errors that cause the white patterns to express slightly differently.

The link below is a to a lively forum discussion of Sabino vs Dominant White. Well worth reading the entire thread if you are interested in the topic.



http://www.equinecolor.com/forum/viewto ... sc&start=0

My two cents is that you have to look at both the phenotype, and how the gene acts.

For example, cream, pearl, dun, and champaign are all genes that modify coat color to a shade of dry grass. However they all work differently and are clearly different genes despite having similar phenotypes.

As a couple folks in the equinecolor thread point out, Sabino 1 works like a recessive with variable expression. Two copies are needed for full expression. Dominant White works like a true dominant, one copy is needed for any level of expression, and no horses with two copies of the mutation have been found.


Thanks for posting that lovely picture of Milkie's Desire. Quite a lovely horse.