The Official "Speed Gene" thread.

Understanding pedigrees, inbreeding, dosage, etc.

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vineyridge
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Postby vineyridge » Mon Feb 27, 2012 6:50 pm

Damn. Just found another hugely influential British sire with a North American dam--Orby. His dam is by Hanover, and she has a lines that go to Sir Archy, Janus, and Croucher. In fact, she has a line that is Janus x Brandon.
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Postby smartyslew » Tue Feb 28, 2012 12:41 am

vineyridge wrote:Damn. Just found another hugely influential British sire with a North American dam--Orby. His dam is by Hanover, and she has a lines that go to Sir Archy, Janus, and Croucher. In fact, she has a line that is Janus x Brandon.


doesn't virgil have all that?
hanovers gr sire virgil 2nd dam little peggys sire cripple
dam is blackburns whip's daughter.2 lines of meades celer
in fact little peggy(usa) is bred to yorkshire (GB) to get virgil
dams hymenia.thats all passed on to hindoo and hanover and
orbys dam..
checkout
hymenias progeny, looks like they had speed
and 2 were sires in texas.. i know nothing about
qh pedigrees.
orbys sire orme has a line of bend or that traces to the skim mare
through thormanby.

vineyridge
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Postby vineyridge » Tue Feb 28, 2012 6:20 am

Yes, Virgil does. But Bend Or was one of the T/T tested stallions.

Atkinson's Shark mare looks more and more interesting to me.

Is there a way to find out if Texas A & M is the institution doing work on the C gene and QHs?
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Postby Elles » Tue Feb 28, 2012 9:58 am

The mare Lucky on Wings I owned for a number of years has this horse in her pedigree: http://www.pedigreequery.com/skymaster.

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Postby Elles » Tue Feb 28, 2012 10:11 am

vineyridge wrote:Atkinson's Shark mare looks more and more interesting to me.


She is behind Lexington (Balls Florizel).
http://trakeny.pl/index.php?strona=konie&kon=dora+wood

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Pan Zareta
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Postby Pan Zareta » Tue Feb 28, 2012 11:13 am

vineyridge wrote:Is there a way to find out if Texas A & M is the institution doing work on the C gene and QHs?


'C' and 'T' are variant alleles at a particular locus in the Myostatin gene complex on ECA18. I don't know if TAMU has any studies focused on MSTN in particular, but a team of researchers there just published a full genome sequencing & variant analysis of a QH mare. That was one of the variants they examined. Ironically(?), the mare was T/T.

http://www.biomedcentral.com/content/pdf/1471-2164-13-78.pdf

smartyslew, the only one of Hymenia's sons that stood in TX was Edinboro/Edinborough. He's in the db under both spellings.

vineyridge
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Postby vineyridge » Tue Feb 28, 2012 12:46 pm

Here is a quote from Dr. Hill's email to me:
You might be interested to know that there is on-going research into this gene in Quarter Horses at another institution, and their research will likely build on the story that we have presented so far.


The research on the QH genome and some other TAMU research on equine genetics is what made me wonder about them.
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Postby smartyslew » Tue Feb 28, 2012 7:25 pm

vineyridge wrote:Yes, Virgil does. But Bend Or was one of the T/T tested stallions.

Atkinson's Shark mare looks more and more interesting to me.

Is there a way to find out if Texas A & M is the institution doing work on the C gene and QHs?


i forgot about bend or, his son ormonde and orme ahead of
orby looks good with orbys dam side and is still a possible.

family 4b keeps popping up: panton spinster, her daughters
grey starling,janus mare,maria-28 1755,and others bay bloody
buttocks and the sires involved,bloody buttocks,crab,second,bolton starling,hautboy, grey hautboy and the family 15 sires,
janus, blank,shakspeare, brabham, and others.

all the family 4 mares trace to 2 barbs layton barb and dodsworth barb
tf 32, going thru greyhound mare-tf 4,1722

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Pan Zareta
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Postby Pan Zareta » Tue Feb 28, 2012 9:36 pm

vineyridge wrote:The research on the QH genome and some other TAMU research on equine genetics is what made me wonder about them.


I wonder about them too, Viney. TAMU is, after all, the institution that used genetic engineering to unleash maroon carrots and maroon bluebonnets on an unsuspecting world. :lol:

More seriously, and regardless of which institution is doing the work, it'll be interesting to learn what effects intense selection for very short speed has had on the MSTN complex in the QH.

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Postby vineyridge » Tue Feb 28, 2012 10:20 pm

Welcome to the SEC where all the other maroon schools will welcome maroon carrots and bluebonnets. :)
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Pan Zareta
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Postby Pan Zareta » Tue Feb 28, 2012 10:50 pm

vineyridge wrote:Welcome to the SEC where all the other maroon schools will welcome maroon carrots and bluebonnets. :)


Good luck to the Aggies in the SEC. Athletically, they're gonna need it.

(It occurs to me that it *could* be the U of Minn that's studying MSTN in the QH. The Equine Center there was the source for the QH control samples in the studies of Hill et al.)

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Postby vineyridge » Wed Feb 29, 2012 7:00 am

The University of Minnesota, TAMU, and University College, Dublin, are members of the international "Equine Genetic Diversity Consortium". TAMU's representative is Gus Cochran and the University of Minnesota list three individuals.
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Postby Pan Zareta » Wed Feb 29, 2012 11:50 am

vineyridge wrote:The University of Minnesota, TAMU, and University College, Dublin, are members of the international "Equine Genetic Diversity Consortium". TAMU's representative is Gus Cochran and the University of Minnesota list three individuals.


Yes, some results of their work were published last month -
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257288/

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Postby vineyridge » Wed Feb 29, 2012 12:21 pm

University of Minnesota is, indeed, doing research on the origins of the c and t alleles in the QH and other breeds and is within a couple of months of publication--per Dr. McCue.

I wonder if she's any kin to Peter McCue? :D
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Postby Pan Zareta » Wed Feb 29, 2012 3:23 pm

vineyridge wrote:University of Minnesota is, indeed, doing research on the origins of the c and t alleles in the QH and other breeds and is within a couple of months of publication--per Dr. McCue.


Good to know. Thanks!

I wonder if she's any kin to Peter McCue? :D


:lol:
(I suspect that the equine P McC was named for a jockey I've run across references to riding at the midwestern tracks in the 1890s.)