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PostPosted: Tue Feb 05, 2019 9:52 am 
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I had the opportunity to write a short article in BlueBloods on the science that is behind pedigree analysis. Thought it would be worth reposting a copy of it here - https://drive.google.com/open?id=1T1hz3JuRAVnzVJqh86nHgyWeAwZNtlRT

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PostPosted: Tue Feb 05, 2019 1:06 pm 
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Suckling

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You're using fighting words for those who use Lowe family numbers as part of research/analysis/breeding decisions!

Good stuff as always, Byron. Is there a publicly available resource for determining Y-chromosome and mtDNA haplotypes across the population (e.g., for stallions and mares since WWII or some other semi-modern cutoff point)? Or is this information available in a reasonably priced genetic testing report if horse owners wished to obtain the data on their breeding and racing stock?

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PostPosted: Tue Feb 05, 2019 9:45 pm 
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Breeder's Cup Winner
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Location: west TX boonies
MaresRest wrote:
...Is there a publicly available resource for determining Y-chromosome and mtDNA haplotypes across the population ...


Lowe family #/mtDNA type cross-reference


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PostPosted: Thu Feb 07, 2019 2:47 pm 
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Suckling

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Thanks, Pan Zareta!


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PostPosted: Sun Feb 10, 2019 12:49 pm 
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I was under the impression that the "anomaly" of King Fergus was due to a mutation in the Y chromosome that occurred between Pot8os and Whalebone, not an error in the sire line. Unless I'm misremembering, DNA testing was done on Eclipse that showed him to carry the same Y as King Fergus.

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PostPosted: Mon Feb 11, 2019 10:21 pm 
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vineyridge wrote:
I was under the impression that the "anomaly" of King Fergus was due to a mutation in the Y chromosome that occurred between Pot8os and Whalebone, not an error in the sire line. Unless I'm misremembering, DNA testing was done on Eclipse that showed him to carry the same Y as King Fergus.


The expected yDNA type for sire line descendants of King Fergus is the Darley type, without the mutation characteristic of sire line descendants of Whalebone. A different yDNA type, the one expected for sire line descendants of the Byerley, is found in modern sire line descendants of St. Simon's sons Persimmon & St. Frusquin (the only descendants of KF tested as of 2017), representing a probable error in the record at or after KF and at or before SS. See Figs. S3 & S4 in Wallner et al. 2017, https://tinyurl.com/y3j3lvf5.

As far as I know, the remains of Eclipse have never been yDNA typed though they were mtDNA typed and screened for a couple of polymorphisms in the recombinant nuclear genome @10 years ago.


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